is Glanzmann's Thrombasthenia?
the free encyclopedia:
thrombasthenia is an extremely rare, autosomal
recessive disorder of the blood, in which the platelets
lack GPIIb/IIIa. Hence, no fibrinogen bridging can occur,
and bleeding time is significantly prolonged. more
Mark you calendars and save March 11,
2006 for the National Science Center's Dinner and Auction
at Fort Discovery in Augusta, Georgia. More information to
October 2005, Vol. 106, No. 8, pp. 2596.
rescue of murine
UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES
integrin receptor is central to the platelet's role in hemostasis
and its absence results in the human bleeding disorder, Glanzmann
thrombasthenia (GT). In this issue of Blood, Fang and colleagues
describe ex vivo viral transduction of mouse hematopoietic
stem cells and determine the in vivo efficiency required to
rescue the GT phenotype in a mouse model of the disorder.
Iron Deficiency Anemia
is still a big problem today. In fact, the World Health Organization
lists iron deficiency as one of the 'Top Ten Risk Factors
Contributing to Death'. more
Jones Business News
Novo Nordisk Says EU OKs NovoSeven For Two
Thursday February 19, 7:49 am ET
- Danish pharmaceuticals company Novo Nordisk A/S said Thursday
the European Commission has approved NovoSeven for two new treatments.
NovoSeven (Eptacog alfa (activated)) was approved for the control
of bleeding in patients with factor VII deficiency and Glanzmanns
thrombasthenia refractory to platelet transfusions. more
British Journal Recommends Immunization for Patients with Bleeding
journal Haemophilia outlined investigators' recommendations
appropriate for patients with bleeding disorders, saying..."
(GT) is caused by a deficiency of a protein on the surface
of the platelet, called Glycoprotein IIb/IIIa. As a result,
platelets fail to form a plug at the site of an injury. more
being done by various organizations. Because of the rarity of
the disease, funds for research are rare also. more
Stories about people
first glance, Julia Smith's curly golden hair, huge
blue eyes and Cupid's bow lips bring to mind a life-size
porcelain doll. But the bruises that dot the 2-year-old's
body from head to toe tell a different story. Julia
was born with a rare, incurable bleeding disorder called
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is a non profit website. The goal of this site is
to provide the general public, parents, loved ones,
and the medical community with accurate information.
All information is taken from sources believed to
be reliable. No treatment of GT should be undertaken
without medical supervision. Donations should be made
to the Glanzmann's
All donations are tax deductible.